Intuitive Surgical, Inc. (ISRG)

Healthcare · Medical Devices · Price $367.07
Updated: Aug 28, 2026
Elevated Multiple — Healthcare
P/E of 42.14x is above the 28x moderate threshold — significant growth expectations already priced in.
P/E Ratio (TTM)
42.14x
Very high P/E - extreme growth expectations or speculative
Earnings Yield
2.37%
1 / P/E Ratio
EPS (TTM)
$8.71
Diluted Earnings Per Share
Stock Price
$367.07
Current Market Price
PEG Ratio
1.98
Moderately priced for growth
Earnings Growth
29.64%
Net Income Growth (Linear)

🧮 ISRG P/E Ratio Calculation

P/E Ratio = Stock Price ÷ Earnings Per Share (TTM)
Stock Price $367.07
÷
Earnings Per Share (TTM) $8.71
= P/E Ratio 42.14x

What is the P/E Ratio?

The Price-to-Earnings (P/E) Ratio is one of the most widely used valuation metrics. It tells you how much investors are willing to pay for each dollar of a company's earnings. Zyberno calculates P/E using trailing twelve month (TTM) diluted earnings from official SEC filings.

P/E Ratio = Stock Price ÷ Earnings Per Share (TTM)
Using diluted EPS which accounts for stock options and convertible securities

How to Interpret the P/E Ratio

Low P/E (Under 15x)

May indicate undervaluation, or the market expects declining earnings. Common in mature, slow-growth industries.

Average P/E (15-20x)

Roughly in line with historical S&P 500 average. Suggests fairly valued with moderate growth expectations.

High P/E (20-35x)

Investors expect above-average earnings growth. Common for technology companies and market leaders.

Very High P/E (35x+)

Extreme growth expectations priced in. Significant valuation risk if growth slows.

PEG Ratio: P/E Adjusted for Growth

The PEG Ratio addresses a key limitation of P/E by factoring in earnings growth. A PEG of 1.0 suggests fair value; below 1.0 may indicate undervaluation, while above 2.0 suggests a premium price for growth.

PEG Ratio = P/E Ratio ÷ Earnings Growth Rate
ISRG: 42.14x ÷ 29.64% = 1.98

P/E Ratio Limitations

The P/E ratio doesn't work for companies with negative earnings. It can be manipulated by one-time charges or gains, and it doesn't account for debt levels or growth rates. Use P/E alongside PEG ratio, EV/EBITDA, and Owner Earnings yield for a complete picture.

Comparing Valuation Metrics

EPS: $8.71 →

The denominator in the P/E calculation. Represents profit allocated to each outstanding share.

Price-to-Book: N/A

Compares stock price to book value. Useful for asset-heavy industries like banking and manufacturing.

EV/EBITDA: N/A

Accounts for debt and is useful for comparing companies with different capital structures.

Owner Earnings Yield →

Warren Buffett's preferred metric. Shows cash return to owners as a percentage of market cap.

📊 Full ISRG Stock Report

Intrinsic value, margin of safety, DCF valuation, and 250+ metrics.

📈 ISRG Earnings Per Share

Deep dive into EPS trends, quarterly history, and earnings growth analysis.

🏆 ISRG ROIC

Measure capital efficiency — how well management deploys every dollar invested.

💎 ISRG Intrinsic Value

Calculate what ISRG is truly worth using DCF and Owner Earnings models.

💵 ISRG Owner Earnings

Warren Buffett's preferred measure of true earning power and cash generation.

🛡️ ISRG Margin of Safety

See if ISRG is trading below its intrinsic value.

View Full ISRG Report Find More Quality Stocks
📊 Valuation Trilogy
Three interconnected metrics built on Owner Earnings
💎
Intrinsic Value
DCF Fair Value
$293.86
🛡️
Margin of Safety
Valuation Gap
-24.9%
🎯
Expected Return
Projected Annual
14.8%
Click any metric for full methodology and detailed analysis

Summary: ISRG P/E Ratio

Intuitive Surgical, Inc. (ISRG) trades at a P/E of 42.14x, which Zyberno classifies as an elevated multiple for a Healthcare company — above the 28x moderate threshold for healthcare companies where pipeline value and patent protection justify premium multiples, with significant growth expectations already priced in. Earnings yield: 2.37%.

Based on 0 quarters of SEC filings, ISRG's EPS is currently $8.71 on a trailing twelve-month basis. Zyberno cross-references the P/E ratio with business quality — a high multiple on a high-quality business (strong ROE, ROIC, and FCF) carries less risk than the same multiple on a weaker business. For complete financial analysis, view the full ISRG stock report on Zyberno.

Frequently Asked Questions

What is ISRG's current P/E Ratio?

Intuitive Surgical, Inc.'s trailing twelve month (TTM) P/E Ratio is 42.14x, within the context of Healthcare sector multiples where Zyberno considers 18–28x moderate. Investors are paying $42.14 for every $1 of annual earnings.

Is ISRG's P/E Ratio high or low?

Intuitive Surgical, Inc. (ISRG) trades at a P/E of 42.14x, which Zyberno classifies as an elevated multiple for a Healthcare company — above the 28x moderate threshold for healthcare companies where pipeline value and patent protection justify premium multiples, with significant growth expectations already priced in. Earnings yield: 2.37%.

What is ISRG's earnings yield?

ISRG's earnings yield is 2.37%, which is the inverse of the P/E ratio (1 ÷ P/E). This represents the theoretical return if all earnings were distributed to shareholders.

How is P/E Ratio calculated?

P/E Ratio = Stock Price ÷ EPS. For ISRG: $367.07 ÷ $8.71 = 42.14x.

What is ISRG's PEG Ratio?

ISRG's PEG Ratio is 1.98. Moderately priced for growth. PEG below 1.0 is often considered undervalued, while above 2.0 may indicate overvaluation relative to growth.

📊 Full ISRG Stock Report

See ISRG's intrinsic value, margin of safety, DCF valuation, and complete financial analysis with 250+ metrics.

🏆 ISRG ROIC

Compare to Return on Invested Capital — the most comprehensive measure of capital efficiency.

📈 ISRG ROE

Compare to Return on Equity and understand the impact of leverage on returns.

🎯 ISRG Earnings Surprise (SUE)

See whether ISRG is beating or missing its own earnings trend — Standardized Unexpected Earnings and post-earnings drift.

👤 ISRG Owner Earnings

Warren Buffett's preferred measure of true economic earnings available to owners.

💰 ISRG Net Income

See the bottom-line profit that drives return calculations.

📊 ISRG EPS

Earnings per share — net income on a per-share basis.

View Full ISRG Report Find More Quality Stocks
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