ARGENX SE (ARGX)

Healthcare · Biological Products, (No Diagnostic Substances) · Price $1,058.90
Updated: Aug 28, 2026
ARGX Stock Rating

Is ARGENX SE a Quality Business?

Analyzing business fundamentals using proven investment principles

36/100
Zyberno Score
Weak Business Quality

Weak fundamentals with mixed indicators requiring careful analysis

About ARGENX SE

argenx SE is a Dutch biopharmaceutical company headquartered in Breda, Netherlands, that develops antibody-based therapies for the treatment of severe autoimmune diseases and cancer. The company's lead product Vyvgart (efgartigimod alfa), which targets the neonatal Fc receptor (FcRn) to reduce pathogenic IgG antibodies, is approved for generalized myasthenia gravis and is being developed across multiple IgG-mediated autoimmune diseases.

📚 How We Measure Business Quality

The Zyberno Score answers one question: "Is this a quality business worth owning?" We analyze 16 fundamental metrics across four key dimensions, using principles from Warren Buffett, Benjamin Graham, Peter Lynch, and Charlie Munger. Each category is worth 25 points for a total of 100.
This score measures business quality only — not whether the stock is cheap, what return you'll get, or when to buy. For that, see the Valuation Trilogy below.

?/25
Profitability
Does it generate strong returns?
Buffett's Focus: High returns on equity and invested capital indicate a durable competitive advantage or "moat." Great businesses earn more with less capital.
Return on Equity (ROE) ROENet income divided by shareholder equity. Measures how efficiently a company uses investor capital to generate profits.Excellent: >20% | Good: >15% N/A
Return on Invested Capital ROICOperating profit divided by total invested capital. Shows how well a company allocates capital to profitable investments.Excellent: >20% | Good: >15% 20.6%
Net Profit Margin Net MarginNet income as a percentage of revenue. Higher margins indicate pricing power and operational efficiency.Excellent: >20% | Good: >12% N/A
Operating Margin Operating MarginOperating income as a percentage of revenue. Measures core business profitability before interest and taxes.Excellent: >25% | Good: >15% N/A
?/25
Financial Strength
Can it survive tough times?
Graham's Principle: Low debt, strong liquidity, and adequate interest coverage protect against bankruptcy and provide stability during economic downturns.
Debt-to-Equity Ratio D/E RatioTotal debt divided by shareholder equity. Lower values indicate less reliance on borrowed money to fund operations.Excellent: <0.3x | Good: <0.5x 0.00x
Current Ratio Current RatioCurrent assets divided by current liabilities. Measures ability to pay short-term obligations within one year.Excellent: >2.0x | Good: >1.5x 5.23x
Interest Coverage Interest CoverageOperating income divided by interest expense. Shows how easily a company can pay interest on its debt.Excellent: >10x | Good: >5x 258.2x
Altman Z-Score Altman Z-ScoreBankruptcy prediction formula combining profitability, leverage, liquidity, and solvency ratios.Safe: >3.0 | Gray zone: 1.8-3.0 N/A
?/25
Cash Flow Quality
Is the profit real?
Munger's Test: "Show me the cash." Accounting profits can be manipulated, but cash flow doesn't lie. Great businesses generate real, spendable cash.
Free Cash Flow Free Cash FlowOperating cash flow minus capital expenditures. The actual cash available after maintaining the business.Excellent: Positive and growing $679.03M
OCF vs Net Income Cash vs EarningsOperating cash flow divided by net income. Values above 1.0 mean cash earnings exceed accounting earnings - a sign of quality.Excellent: >1.2x | Good: >1.0x 0.53x
FCF Margin FCF MarginFree cash flow as a percentage of revenue. Shows how much real cash profit is generated per dollar of sales.Excellent: >15% | Good: >10% N/A
Cash Conversion Cycle Cash ConversionDays between paying suppliers and receiving cash from customers. Lower is better - means faster cash collection.Excellent: <30 days | Good: <60 days 79 days
?/25
Growth & Consistency
Is it getting better?
Lynch's Approach: Sustainable growth matters. We use log-linear regression to identify consistent long-term trends, not just year-over-year noise.
Revenue Growth (5yr) Revenue GrowthAnnualized revenue growth rate using log-linear regression over 5 years. Smooths out year-to-year volatility.Excellent: >15% | Good: >10% N/A
Net Income Growth (5yr) Profit GrowthAnnualized net income growth rate using log-linear regression. Shows whether profits are consistently expanding.Excellent: >15% | Good: >10% N/A
FCF Growth (5yr) Cash Flow GrowthAnnualized free cash flow growth rate. Growing FCF means the business generates more real cash over time.Excellent: >15% | Good: >10% N/A
Piotroski F-Score Piotroski F-Score9-point checklist measuring profitability, leverage, and efficiency improvements. Higher scores indicate stronger fundamentals.Excellent: 8-9 | Good: 6-7 N/A

💡 Quality Is Only Half the Picture

A high quality score means ARGX shows strong business fundamentals. But even the best business can be a poor investment at the wrong price. As Warren Buffett says: "Price is what you pay, value is what you get."

To complete your analysis, examine our Valuation Trilogy:

💎
Intrinsic Value
What is the business actually worth?
🛡
Margin of Safety
How much discount are you getting?
🎯
Expected Annual Return
What return might you earn?

📈 Price Action Check

Market trend context — not part of the Zyberno Score

12-1 Momentum
+37.0%
Momentum Percentile
87 / 100
% of 52-Week High
117.3%
Strong Momentum

The market has been actively rewarding ARGX over the past year. Strong momentum on a quality business usually means the story is already being recognised — check the valuation signals above before paying up. Full momentum analysis →

View Full ARGX Report Find More Quality Stocks

Conclusion: Is ARGX a Good Stock?

According to Zyberno's analysis, ARGENX SE (ARGX) is a Weak Business, earning a Zyberno Score of 36/100.

What drives ARGX's score

Zyberno's analysis of ARGX's fundamentals identifies the following key drivers. ROIC of 20.6% comfortably exceeds the cost of capital for most businesses, signaling that ARGENX SE creates significant value on every dollar of capital deployed. With a debt-to-equity ratio of 0.00x, ARGENX SE carries minimal leverage — a sign of financial conservatism that reduces risk in economic downturns. An interest coverage ratio of 258.2x means ARGENX SE earns 258 times more operating income than it needs to service its debt — a strong indicator of financial safety.

The Brina Gap measures the difference between the growth a business can fundamentally sustain and the growth the market is already pricing in. ARGENX SE's Brina Gap is -25.9% — the enterprise value implies the market expects much faster growth than the business can actually deliver based on its return on invested capital and reinvestment rate. This is a strong signal that forward compounding capacity is being significantly overestimated.

Zyberno's score and valuation reflect the direct output of the model — business quality from fundamentals, margin of safety from owner earnings, Brina Gap from the reverse DCF. The numbers are not adjusted toward the current price, analyst ratings, or market sentiment. The score measures the quality of the business. The valuation measures the price you pay for it.

Zyberno Verdict

According to Zyberno's model, ARGENX SE (ARGX) is a Weak Business with a Zyberno Score of 36/100.

❓ Frequently Asked Questions

What does ARGX's Zyberno Score of 36/100 mean?

According to Zyberno's scoring model, a score of 36/100 places ARGENX SE in the Weak Business category — weak fundamentals with mixed indicators requiring careful analysis. Zyberno's model scores 75–100 as excellent, 65–74 as good, 50–64 as average, 30–49 as below average, and below 30 as poor, based on the investment frameworks of Buffett, Graham, Lynch, and Munger. Note that a high quality score measures business fundamentals, not whether the stock is currently priced attractively — for that, see the margin of safety analysis.

What makes a stock "high quality"?

A high-quality stock typically exhibits: strong returns on equity and invested capital (indicating competitive advantages), healthy profit margins, low debt levels, ample liquidity, consistent cash flow generation, and sustainable growth. We analyze 16 key metrics across four categories - Profitability (ROE, ROIC, margins), Financial Strength (debt, liquidity, coverage), Cash Flow Quality (FCF, OCF vs earnings), and Growth & Consistency (revenue/profit trends, Piotroski score) - drawing from the investment philosophies of Buffett, Graham, Lynch, and Munger.

How is the quality score different from a stock rating?

Our quality score measures business fundamentals - how well the company operates, generates profits, and maintains financial health. Unlike analyst "buy/sell" ratings, we don't tell you whether to purchase the stock. A company can have excellent quality (great business) but poor investment potential (if overpriced), or vice versa. For valuation analysis, see our Margin of Safety page.

Why do you use Owner Earnings instead of regular earnings?

Owner Earnings, a concept popularized by Warren Buffett, represents the true cash available to shareholders after maintaining the business. Unlike accounting earnings, which can be manipulated through depreciation schedules and accruals, Owner Earnings = Operating Cash Flow minus Maintenance Capital Expenditures. This gives a clearer picture of what a business actually generates for its owners. Learn more about ARGX's Owner Earnings.

How often is the quality score updated?

Quality scores are recalculated whenever new financial data becomes available, typically after quarterly earnings reports. The underlying metrics (ROE, ROIC, debt ratios, etc.) come from company filings and are updated as soon as they're reported. For the most comprehensive and up-to-date data, visit the full ARGX stock report.

📊 Full ARGX Stock Report

Complete financial data, charts, all 250+ metrics, and detailed analysis for ARGENX SE.

🎯 ARGX Earnings Surprise (SUE)

See whether ARGENX SE is beating or missing its own earnings trend — Standardized Unexpected Earnings and post-earnings drift.

🔍 Stock Screener

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DISCLAIMER: Zyberno's financial tools, stock screeners, investment calculators, and market indicators are for educational purposes only and do not constitute financial advice. Data may be delayed, incomplete, or inaccurate. All investments involve risk, including loss of principal. Past performance of stocks and other securities does not guarantee future results. Before making investment decisions, consult with a qualified financial professional.
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